TBX3 Polyclonal Antibody

Ab type

Primary antibody

Background

TBX3 (T-box 3) is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This protein is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in TBX3 cause ulnar-mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing of TBX3 results in three transcript variants encoding different isoforms; however, the full length nature of one variant has not been determined.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human TBX3. AA range:301-350

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

79389

synonyms

TBX3; T-box transcription factor TBX3; T-box protein 3