TBP Antibody

Size

100ug

Clone Number

Aliases

GTF2D antibody; GTF2D1 antibody; HDL4 antibody; MGC117320 antibody; MGC126054 antibody; MGC126055 antibody; SCA17 antibody; TATA binding factor antibody; TATA box factor antibody; TATA sequence binding protein antibody; TATA sequence-binding protein antibody; TATA-binding factor antibody; TATA-box binding protein N-terminal domain antibody; TATA-box factor antibody; TATA-box-binding protein antibody; TBP antibody; TBP_HUMAN antibody; TFIID antibody; Transcription initiation factor TFIID TBP subunit antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P20226

Immunogen

Recombinant Human TATA-box-binding protein (1-55AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

Background

General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1 with the rDNA promoter. SL1 is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

TBP

Research Areas

Isotype/Loading Controls; Epigenetics and Nuclear Signaling