TBL1XR1 Antibody

Size

100ul

Clone Number

Aliases

C21 antibody; DC42 antibody; F box like/WD repeat containing protein TBL1XR1 antibody; F-box-like/WD repeat-containing protein TBL1XR1 antibody; FLJ12894 antibody; IRA1 antibody; Nuclear receptor corepressor/HDAC3 complex subunit antibody; Nuclear receptor corepressor/HDAC3 complex subunit TBLR1 antibody; TBL1 related protein 1 antibody; TBL1-related protein 1 antibody; TBL1R_HUMAN antibody; TBL1XR1 antibody; TBLR1 antibody; Transducin (beta) like 1 X linked receptor 1 antibody; Transducin beta like 1X related protein 1 antibody; Transducin beta-like 1X-related protein 1 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9BZK7

Immunogen

Recombinant Human F-box-like/WD repeat-containing protein TBL1XR1 protein (1-180AA)

Raised in

Rabbit

Species Reactivity

Human, Mouse

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200

Background

F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of the N-Cor corepressor complex that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of N-Cor complex, thereby allowing cofactor exchange, and transcription activation.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

TBL1XR1

Research Areas

Epigenetics and Nuclear Signaling; Cancer; Metabolism