TBK1/NAK(Phospho-Ser172) Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins| which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway| thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors.

Reactivity

Human, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized phosho peptide around human TBK1 and NAK (Ser172)

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

synonyms

TBK1/NAK ;Ser172 ; Serine/threonine-protein kinase TBK1; EC 2.7.11.1; NF-kappa-B-activating kinase; T2K; TANK-binding kinase 1