Tau(Phospho-Ser416) Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex| regulated alternative splicing| giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system| depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease| Pick's disease| frontotemporal dementia| cortico-basal degeneration and progressive supranuclear palsy.

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized phosho peptide around human Tau (Ser416)

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

synonyms

Tau ;Ser416 ; Microtubule-associated protein tau; Neurofibrillary tangle protein; Paired helical filament-tau; PHF-tau