TANK Antibody, Biotin conjugated

Size

100ug

Clone Number

Aliases

I TRAF antibody; I-TRAF antibody; ITRAF antibody; Tank antibody; TANK_HUMAN antibody; TRAF family member associated NF KAPPA B activator antibody; TRAF family member associated NFKB activator antibody; TRAF family member-associated NF-kappa-B activator antibody; TRAF interacting protein antibody; TRAF interacting protein TANK isoform a antibody; TRAF interacting protein TANK isoform b antibody; TRAF-interacting protein antibody; TRAF2 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q92844

Immunogen

Recombinant Human TRAF family member-associated NF-kappa-B activator protein (4-98AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA

Background

Adapter protein involved in I-kappa-B-kinase (IKK) regulation which constitutively binds TBK1 and IKBKE playing a role in antiviral innate immunity. Acts as a regulator of TRAF function by maintaining them in a latent state. Blocks TRAF2 binding to LMP1 and inhibits LMP1-mediated NF-kappa-B activation. May control negatively TRAF2-mediated NF-kappa-B activation signaled by CD40, TNFR1 and TNFR2.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Biotin

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

TANK

Research Areas

Immunology; Signal transduction