Tafazzin Polyclonal Antibody

Ab type

Primary antibody

Background

TAZ (tafazzin) encodes a protein that is expressed at high levels in cardiac and skeletal muscle. Mutations in TAZ have been associated with a number of clinical disorders including Barth syndrome, dilated cardiomyopathy (DCM), hypertrophic DCM, endocardial fibroelastosis, and left ventricular noncompaction (LVNC). Multiple transcript variants encoding different isoforms have been described. A long form and a short form of each of these isoforms is produced; the short form lacks a hydrophobic leader sequence and may exist as a cytoplasmic protein rather than being membrane-bound. Other alternatively spliced transcripts have been described but the full-length nature of all these transcripts is not known.

Reactivity

Human

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from the Internal region of human Tafazzin.

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

33459

synonyms

TAZ; EFE2; G4.5; Tafazzin; Protein G4.5