ABCbiolab
SKU:ABCCS45083
TAF1C Antibody
TAF1C Antibody
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Size
100ul
Clone Number
Aliases
RNA polymerase I-specific TBP-associated factor 110 kDa antibody; SL1 antibody; Taf1c antibody; TAF1C_HUMAN antibody; TAFI110 antibody; TAFI95 antibody; TATA box binding protein associated factor 1C antibody; TATA box-binding protein-associated factor 1C antibody; TATA box-binding protein-associated factor RNA polymerase I subunit C antibody; TBP associated factor 1C antibody; TBP associated factor RNA polymerase I 95 kDa antibody; TBP associated factor; RNA polymerase I; 110-KD antibody; TBP-associated factor 1C antibody; Transcription initiation factor SL1/TIF-IB subunit C antibody
Immunogen Species
Homo sapiens (Human)
UniProt ID
Q15572
Immunogen
Recombinant Human TATA box-binding protein-associated factor RNA polymerase I subunit C protein (70-320AA)
Raised in
Rabbit
Species Reactivity
Human
Tested Applications
ELISA, WB, IHC; Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200
Background
Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits. Recruits RNA polymerase I to the rRNA gene promoter via interaction with RRN3.
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Stroage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names
TAF1C
Research Areas
Epigenetics and Nuclear Signaling
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