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ABCbiolab

SKU:ABCCS45083

TAF1C Antibody

TAF1C Antibody

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Size

100ul

Clone Number

Aliases

RNA polymerase I-specific TBP-associated factor 110 kDa antibody; SL1 antibody; Taf1c antibody; TAF1C_HUMAN antibody; TAFI110 antibody; TAFI95 antibody; TATA box binding protein associated factor 1C antibody; TATA box-binding protein-associated factor 1C antibody; TATA box-binding protein-associated factor RNA polymerase I subunit C antibody; TBP associated factor 1C antibody; TBP associated factor RNA polymerase I 95 kDa antibody; TBP associated factor; RNA polymerase I; 110-KD antibody; TBP-associated factor 1C antibody; Transcription initiation factor SL1/TIF-IB subunit C antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q15572

Immunogen

Recombinant Human TATA box-binding protein-associated factor RNA polymerase I subunit C protein (70-320AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200

Background

Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits. Recruits RNA polymerase I to the rRNA gene promoter via interaction with RRN3.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

TAF1C

Research Areas

Epigenetics and Nuclear Signaling

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