syntenin Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

The protein encoded by this gene was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic| C-terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal-membrane organization| cell adhesion| protein trafficking| and the activation of transcription factors. The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus. Alternative splicing results in multiple transcript variants encoding different isoforms.

Reactivity

Human, Rat, Dog, Pig

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human syntenin

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

32780

synonyms

syntenin; Syntenin-1; Melanoma differentiation-associated protein 9; MDA-9; Pro-TGF-alpha cytoplasmic domain-interacting protein 18; TACIP18; Scaffold protein Pbp1; Syndecan-binding protein 1