SYNM Antibody

Size

100ug

Clone Number

Aliases

Desmuslin antibody; DMN antibody; KIAA0353 antibody; SYN antibody; SYNEM_HUMAN antibody; Synemin alpha antibody; Synemin antibody; Synemin beta antibody; Synemin; intermediate filament protein antibody; SYNM antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

O15061

Immunogen

Recombinant Human Synemin protein (1147-1417AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

Background

Type-VI intermediate filament (IF) which plays an important cytoskeletal role within the muscle cell cytoskeleton. It forms heteropolymeric IFs with desmin and/or vimentin, and via its interaction with cytoskeletal proteins alpha-dystrobrevin, dystrophin, talin-1, utrophin and vinculin, is able to link these heteropolymeric IFs to adherens-type junctions, such as to the costameres, neuromuscular junctions, and myotendinous junctions within striated muscle cells.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

SYNM

Research Areas

Signal transduction