Syk(Phospho Tyr525) Polyclonal Antibody

Ab type

Primary antibody

Background

This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Reactivity

Human, Mouse, Rat, Monkey

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human SYK around the phosphorylation site of Tyr525. AA range:491-540

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

72066

synonyms

Tyrosine-protein kinase SYK; SYK; Tyrosine-protein kinase SYK; Spleen tyrosine kinase; p72-Syk