SWAP70 Antibody

Size

100ug

Clone Number

Aliases

KIAA0640 antibody; 70kDa antibody; AV235546 antibody; FLJ39540 antibody; HSPC321 antibody; SWA 70 protein antibody; SWAP 70 antibody; SWAP switching B-cell complex 70kDa subunit antibody; SWAP-70 antibody; SWAP70 antibody; Switch associated protein 70 antibody; Switch-associated protein 70 antibody; SWP70_HUMAN antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9UH65

Immunogen

Recombinant Human Switch-associated protein 70 protein (1-300AA)

Raised in

Rabbit

Species Reactivity

Human, Mouse

Tested Applications

ELISA, WB; Recommended dilution: WB:1:500-1:2000

Background

Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

SWAP70

Research Areas

Immunology; Signal transduction