SURF-1 Polyclonal Antibody

Ab type

Primary antibody

Background

SURF1 encodes surfeit locus protein 1 localized to the inner mitochondrial membrane and thought to be involved in the biogenesis of the cytochrome c oxidase complex. Surfeit locus protein 1 is a member of the SURF1 family, which includes the related yeast protein SHY1 and rickettsial protein RP733. The gene is located in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity, where it shares a bidirectional promoter with SURF2 on the opposite strand. Defects in this gene are a cause of Leigh syndrome, a severe neurological disorder that is commonly associated with systemic cytochrome c oxidase deficiency.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human SURF1. AA range:171-220

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

33331

synonyms

SURF1; SURF-1; Surfeit locus protein 1