SUN1 Antibody, Biotin conjugated

Size

100ul

Clone Number

Aliases

SUN1 antibody; At5g04990 antibody; MUG13.15 antibody; SUN domain-containing protein 1 antibody; AtSUN1 antibody

Immunogen Species

Arabidopsis thaliana

UniProt ID

Q9FF75

Immunogen

Recombinant Arabidopsis thaliana SUN domain-containing protein 1 protein (2-105AA)

Raised in

Rabbit

Species Reactivity

Arabidopsis thaliana

Tested Applications

ELISA

Background

Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments (PubMed: 24667841, PubMed: 25759303). Required for the maintenance and/or formation of polarized nuclear shape in root hairs (PubMed: 21294795, PubMed: 25759303). Modulates the anchoring and mobility of WIP proteins and RANGAP1 in the nuclear envelope (NE) (PubMed: 22270916). In association with SUN2, may be involved in telomere attachment to nuclear envelope in the prophase of meiosis (PubMed: 25412930). As component of the SUN-WIP-WIT2-KAKU1 complex, mediates the transfer of cytoplasmic forces to the nuclear envelope (NE), leading to nuclear shape changes (PubMed: 25759303).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Biotin

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

SUN1

Research Areas

Tags & Cell Markers; Epigenetics and Nuclear Signaling