STXBP4 Antibody

Size

100ul

Clone Number

Aliases

FLJ16496 antibody; MGC149829 antibody; MGC50337 antibody; OTTHUMP00000082667 antibody; OTTHUMP00000227400 antibody; STX4-interacting protein antibody; STXB4_HUMAN antibody; Stxbp4 antibody; Synip antibody; Syntaxin 4 interacting protein antibody; Syntaxin 4-interacting protein antibody; Syntaxin binding protein 4 antibody; Syntaxin-binding protein 4 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q6ZWJ1

Immunogen

Recombinant Human Syntaxin-binding protein 4 protein (344-553AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB; Recommended dilution: WB:1:500-1:5000

Background

Plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane. Inhibits the translocation of SLC2A4 from intracellular vesicles to the plasma membrane by STX4A binding and preventing the interaction between STX4A and VAMP2. Stimulation with insulin disrupts the interaction with STX4A, leading to increased levels of SLC2A4 at the plasma membrane. May also play a role in the regulation of insulin release by pancreatic beta cells after stimulation by glucose .

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

STXBP4

Research Areas

Metabolism; Signal transduction