STOML2 Antibody

Size

100ul

Clone Number

Aliases

EPB72 like protein 2 antibody; EPB72-like protein 2 antibody; HSPC108 antibody; OTTHUMP00000021320 antibody; Paraprotein target 7 antibody; Paratarg 7 antibody; SLP 2 antibody; SLP-2 antibody; SLP2 antibody; STML2_HUMAN antibody; Stomatin (EPB72) like 2 antibody; Stomatin like 2 antibody; Stomatin like protein 2 antibody; Stomatin like protein 2, mitochondrial antibody; Stomatin-like protein 2 antibody; STOML2 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9UJZ1

Immunogen

Recombinant Human Stomatin-like protein 2, mitochondrial protein (29-356AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Mitochondrial protein that probably regulates the biogenesis and the activity of mitochondria. Stimulates cardiolipin biosynthesis, binds cardiolipin-enriched membranes where it recruits and stabilizes some proteins including prohibitin and may therefore act in the organization of functional microdomains in mitochondrial membranes. Through regulation of the mitochondrial function may play a role into several biological processes including cell migration, cell proliferation, T-cell activation, calcium homeostasis and cellular response to stress. May play a role in calcium homeostasis through negative regulation of calcium efflux from mitochondria. Required for mitochondrial hyperfusion a pro-survival cellular response to stress which results in increased ATP production by mitochondria. May also regulate the organization of functional domains at the plasma membrane and play a role in T-cell activation through association with the T-cell receptor signaling complex and its regulation.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

STOML2

Research Areas

Cancer