STK36 Polyclonal Antibody

Ab type

Primary antibody

Background

STK36 encodes a member of the serine/threonine kinase family of enzymes. This family member is similar to a Drosophila protein that plays a key role in the Hedgehog signaling pathway. This human protein is a positive regulator of the GLI zinc-finger transcription factors. Knockout studies of the homologous mouse gene suggest that defects in this human gene may lead to congenital hydrocephalus, possibly due to a functional defect in motile cilia. Because Hedgehog signaling is frequently activated in certain kinds of gastrointestinal cancers, it has been suggested that STK36 is a target for the treatment of these cancers. Alternative splicing of this gene results in multiple transcript variants.

Reactivity

Human;Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human STK36. AA range:387-436

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

143995

synonyms

STK36; KIAA1278; Serine/threonine-protein kinase 36; Fused homolog