STAM2(Phospho Tyr192) Polyclonal Antibody

Ab type

Primary antibody

Background

The protein encoded by this gene is closely related to STAM| an adaptor protein involved in the downstream signaling of cytokine receptors| both of which contain a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM). Similar to STAM| this protein acts downstream of JAK kinases| and is phosphorylated in response to cytokine stimulation. This protein and STAM thus are thought to exhibit compensatory effects on the signaling pathway downstream of JAK kinases upon cytokine stimulation.

Reactivity

Human, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human STAM2 around the phosphorylation site of Tyr192. AA range:161-210

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

58164

synonyms

Signal transducing adapter molecule 2; STAM2; HBP; Signal transducing adapter molecule 2; STAM-2; Hrs-binding protein