STAG3 Antibody

Size

100ug

Clone Number

Aliases

STAG3 antibody; Cohesin subunit SA-3 antibody; SCC3 homolog 3 antibody; Stromal antigen 3 antibody; Stromalin-3 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9UJ98

Immunogen

Recombinant Human Cohesin subunit SA-3 protein (1056-1212AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:200-1:500

Background

Meiosis specific component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

STAG3

Research Areas

Epigenetics and Nuclear Signaling; Cell biology