STAB2 Antibody

Size

100ul

Clone Number

Aliases

190 kDa form stabilin-2 antibody; 190 kDa hyaluronan receptor for endocytosis antibody; EGF-like antibody; FAS1 EGF-like and X-link domain-containing adhesion molecule 2 antibody; Fasciclin antibody; FEEL-2 antibody; FEEL2 antibody; FELL antibody; FEX2 antibody; HARE antibody; Hyaluronan receptor for endocytosis antibody; laminin-type EGF-like and link domain-containing scavenger receptor 2 antibody; link domain-containing scavenger receptor 2 antibody; STAB-2 antibody; Stab2 antibody; STAB2_HUMAN antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q8WWQ8

Immunogen

Recombinant Human Stabilin-2 protein (1550-1850AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Hyaluronan receptor that binds to and mediates endocytosis of hyaluronic acid (HA). Acts also, in different species, as a primary systemic scavenger receptor for heparin (Hep), chondroitin sulfate (CS), dermatan sulfate (DS), nonglycosaminoglycan (GAG), acetylated low-density lipoprotein (AcLDL), pro-collagen propeptides and advanced glycation end products (AGE). May serve to maintain tissue integrity by supporting extracellular matrix turnover or it may contribute to maintaining fluidity of bodily liquids by resorption of hyaluronan. Counter receptor which plays an important role in lymphocyte recruitment in the hepatic vasculature. Binds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection. The proteolytically processed 190 kDa form also functions as an endocytosis receptor for heparin internalisation as well as HA and CS.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

STAB2

Research Areas

Signal transduction; Stem cells