SREBF1 Antibody, Biotin conjugated

Size

100ug

Clone Number

Aliases

ADD 1 antibody; bHLHd1 antibody; Class D basic helix-loop-helix protein 1 antibody; D630008H06 antibody; Processed sterol regulatory element-binding protein 1 antibody; SRBP1_HUMAN antibody; SREBF 1 antibody; SREBF1 antibody; SREBP 1 antibody; SREBP 1c antibody; SREBP-1 antibody; SREBP1 antibody; Sterol regulatory element binding protein 1 antibody; Sterol Regulatory Element Binding Transcription Factor 1 / Protein 1 antibody; Sterol regulatory element binding transcription factor 1 antibody; Sterol regulatory element-binding transcription factor 1 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P36956

Immunogen

Recombinant Human Sterol regulatory element-binding protein 1 protein (38-201AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA

Background

Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the fatty acid and to a lesser degree the cholesterol synthesis pathway (By similarity). Binds to the sterol regulatory element 1 (SRE-1) (5\'-ATCACCCCAC-3\'). Has dual sequence specificity binding to both an E-box motif (5\'-ATCACGTGA-3\') and to SRE-1 (5\'-ATCACCCCAC-3\').

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Biotin

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

SREBF1

Research Areas

Epigenetics and Nuclear Signaling; Cancer; Cardiovascular; Metabolism