SREBF1 Antibody

Size

100ug

Clone Number

Aliases

ADD 1 antibody; bHLHd1 antibody; Class D basic helix-loop-helix protein 1 antibody; D630008H06 antibody; Processed sterol regulatory element-binding protein 1 antibody; SRBP1_HUMAN antibody; SREBF 1 antibody; SREBF1 antibody; SREBP 1 antibody; SREBP 1c antibody; SREBP-1 antibody; SREBP1 antibody; Sterol regulatory element binding protein 1 antibody; Sterol Regulatory Element Binding Transcription Factor 1 / Protein 1 antibody; Sterol regulatory element binding transcription factor 1 antibody; Sterol regulatory element-binding transcription factor 1 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P36956

Immunogen

Recombinant Human Sterol regulatory element-binding protein 1 protein (38-201AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IHC, IF; Recommended dilution: WB:1:1000-1:5000, IHC:1:200-1:500, IF:1:50-1:200

Background

Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the fatty acid and to a lesser degree the cholesterol synthesis pathway (By similarity). Binds to the sterol regulatory element 1 (SRE-1) (5\\\'-ATCACCCCAC-3\\\'). Has dual sequence specificity binding to both an E-box motif (5\\\'-ATCACGTGA-3\\\') and to SRE-1 (5\\\'-ATCACCCCAC-3\\\').

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

SREBF1

Research Areas

Epigenetics and Nuclear Signaling; Cancer; Cardiovascular; Metabolism