SPN Antibody

Size

100ul

Clone Number

Aliases

CD 43 antibody; CD43 antibody; CD43 antigen antibody; Galactoglycoprotein antibody; GALGP antibody; GPL 115 antibody; GPL115 antibody; Human gene for sialophorin antibody; Leucocyte sialoglycoprotein antibody; LEUK_HUMAN antibody; Leukocyte large sialoglycoprotein antibody; Leukocyte sialoglycoprotein antibody; Leukosialin antibody; LSN antibody; Ly-48 antibody; sialophorin (gpL115, leukosialin, CD43) antibody; Sialophorin antibody; Spn antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P16150

Immunogen

Recombinant Human Leukosialin protein (276-400AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

One of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter-receptor for SN/Siglec-1 (By similarity). During T-cell activation is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response .

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

SPN

Research Areas

Immunology; Stem cells