speB Antibody

Size

100ug

Clone Number

Aliases

speB antibody; M28_Spy1721 antibody; Streptopain antibody; EC 3.4.22.10 antibody; Exotoxin type B antibody; SPE B antibody; Streptococcal cysteine proteinase antibody; Streptococcus peptidase A antibody; SPP antibody

Immunogen Species

Streptococcus pyogenes serotype M28

UniProt ID

Q48R29

Immunogen

Recombinant Streptococcus pyogenes serotype M28 Streptopain protein (146-398AA)

Raised in

Rabbit

Species Reactivity

Streptococcus pyogenes serotype M28

Tested Applications

ELISA, WB; Recommended dilution: WB:1:500-1:5000

Background

Important streptococcal virulence factor which cleaves human fibronectin and degrades vitronectin. Also cleaves human IL1B precursor to form biologically active IL1B. Can induce apoptosis in human monocytes and epithelial cells in vitro, and reduces phagocytic activity in monocytic cells. Thus, may play a role in bacterial colonization, invasion, and inhibition of wound healing (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

speB

Research Areas

Others