SPARC Polyclonal Antibody

Ab type

Primary antibody

Background

SPARC encodes a cysteine-rich acidic matrix-associated protein. The secreted protein acidic and cysteine rich is required for the collagen in bone to become calcified but is also involved in extracellular matrix synthesis and promotion of changes to cell shape. The gene product has been associated with tumor suppression but has also been correlated with metastasis based on changes to cell shape which can promote tumor cell invasion. Three transcript variants encoding different isoforms have been found for this gene.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from the Internal region of human SPARC. AA range:141-190

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

33330

synonyms

SPARC; ON; SPARC; Basement-membrane protein 40; BM-40; Osteonectin; ON; Secreted protein acidic and rich in cysteine