SP3 Antibody

Size

100ug

Clone Number

Aliases

D130027J01Rik antibody; DKFZp686O1631 antibody; GC binding transcription factor Sp 3 antibody; GC binding transcription factor Sp3 antibody; MGC105187 antibody; OTTMUSP00000014207 antibody; SP 3 antibody; Sp 3 transcription factor antibody; SP3 antibody; Sp3 transcription factor antibody; SP3_HUMAN antibody; Specificity protein 3 antibody; SPR 2 antibody; SPR-2 antibody; SPR2 antibody; Transcription factor SP 3 antibody; Transcription factor Sp3 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q02447

Immunogen

Recombinant Human Transcription factor Sp3 protein (301-384AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:500-1:1000

Background

Transcriptional factor that can act as an activator or repressor depending on isoform and/or post-translational modifications. Binds to GT and GC boxes promoter elements. Competes with SP1 for the GC-box promoters. Weak activator of transcription but can activate a number of genes involved in different processes such as cell-cycle regulation, hormone-induction and house-keeping.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

SP3

Research Areas

Epigenetics and Nuclear Signaling