Sp1 Polyclonal Antibody

Ab type

Primary antibody

Background

Transcription factor Sp1 encoded by SP1 is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human SP1. AA range:706-755

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

80693

synonyms

SP1; TSFP1; Transcription factor Sp1