SOX17 Antibody, HRP conjugated

Size

100ug

Clone Number

Aliases

FLJ22252 antibody; SOX17 antibody; SOX17_HUMAN antibody; SRY (sex determining region Y) box 17 antibody; SRY box 17 antibody; SRY related HMG box transcription factor SOX17 antibody; Transcription factor SOX-17 antibody; Transcription factor SOX17 antibody; VUR3 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9H6I2

Immunogen

Recombinant Human Transcription factor SOX-17 protein (177-414AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA

Background

Acts as transcription regulator that binds target promoter DNA and bends the DNA. Binds to the sequences 5\'-AACAAT-\'3 or 5\'-AACAAAG-3\'. Modulates transcriptional regulation via WNT3A. Inhibits Wnt signaling. Promotes degradation of activated CTNNB1. Plays a key role in the regulation of embryonic development. Required for normal looping of the embryonic heart tube. Required for normal development of the definitive gut endoderm. Probable transcriptional activator in the premeiotic germ cells (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

HRP

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

SOX17

Research Areas

Epigenetics and Nuclear Signaling; Developmental biology; Stem cells