Sox-12 Polyclonal Antibody

Ab type

Primary antibody

Background

Members of the SOX family of transcription factors are characterized by the presence of a DNA-binding high mobility group (HMG) domain, homologous to the HMG box of sex-determining region Y (SRY). Forming a subgroup of the HMG domain superfamily, SOX proteins have been implicated in cell fate decisions in a diverse range of developmental processes. SOX transcription factors have diverse tissue-specific expression patterns during early development and have been proposed to act as target-specific transcription factors and/or as chromatin structure regulatory elements. The protein encoded by SOX12 (SRY-box 12) was identified as a SOX family member based on conserved domains, and its expression in various tissues suggests a role in both differentiation and maintenance of several cell types.

Reactivity

Human;Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human SOX12. AA range:71-120

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

34122

synonyms

SOX12; SOX22; Transcription factor SOX-12; Protein SOX-22