SOS1 Antibody

Size

100ug

Clone Number

Aliases

alternate SOS1 antibody; GF1 antibody; GGF1 antibody; GINGF antibody; gingival fibromatosis antibody; gingival fibromatosis hereditary 1 antibody; Guanine nucleotide exchange factor antibody; HGF antibody; NS4 antibody; Son of sevenless homolog 1 (Drosophila) antibody; Son of sevenless homolog 1 antibody; SOS Ras/Rac guanine nucleotide exchange factor 1 antibody; SOS-1 antibody; Sos1 antibody; SOS1_HUMAN antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q07889

Immunogen

Recombinant Human Son of sevenless homolog 1 protein (1140-1281AA)

Raised in

Rabbit

Species Reactivity

Human, Rat

Tested Applications

ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500, IF:1:50-1:200

Background

Promotes the exchange of Ras-bound GDP by GTP (PubMed:8493579). Probably by promoting Ras activation, regulates phosphorylation of MAP kinase MAPK3 in response to EGF (PubMed:17339331). Catalytic component of a trimeric complex that participates in transduction of signals from Ras to Rac by promoting the Rac-specific guanine nucleotide exchange factor (GEF) activity (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

SOS1

Research Areas

Cancer; Signal transduction