SOD1 Polyclonal Antibody

Ab type

Primary antibody

Background

The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from the Internal region of human SOD-1.

Storage Stability

-20°C for 1 year

Concentration

MolecularWeight_Da

synonyms

Superoxide dismutase [Cu-Zn]; SOD1; Superoxide dismutase [Cu-Zn; ; Superoxide dismutase 1; hSod1