SOD-1 Polyclonal Antibody

Ab type

Primary antibody

Background

Superoxide dismutase [Cu-Zn] encoded by SOD1 binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human SOD-1. AA range:36-85

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

15936

synonyms

SOD1; Superoxide dismutase [Cu-Zn]; Superoxide dismutase 1; hSod1