SOCS6 Antibody

Size

100ul

Clone Number

Aliases

CIS-4 antibody; CIS4 antibody; Cish4 antibody; Cytokine inducible SH2 protein 4 antibody; Cytokine-inducible SH2 protein 4 antibody; HSPC060 antibody; SOCS-4 antibody; SOCS-6 antibody; SOCS4 antibody; Socs6 antibody; SOCS6_HUMAN antibody; SSI4 antibody; STAI4 antibody; STAT induced STAT inhibitor 4 antibody; STAT4 antibody; STATI4 antibody; Suppressor of cytokine signaling 4 antibody; Suppressor of cytokine signaling 6 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

O14544

Immunogen

Recombinant Human Suppressor of cytokine signaling 6 protein (1-210AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

Background

SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Regulates KIT degradation by ubiquitination of the tyrosine-phosphorylated receptor.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

SOCS6

Research Areas

Epigenetics and Nuclear Signaling; Signal transduction