SOCS4 Antibody

Size

100ul

Clone Number

Aliases

CIS4 antibody; Cish4 antibody; Cytokine inducible SH2 protein 4 antibody; DKFZp686J1568 antibody; HSPC060 antibody; SH2 domain containing SOCS box protein antibody; SOCS-4 antibody; SOCS-7 antibody; SOCS4 antibody; SOCS4_HUMAN antibody; SOCS6 antibody; SOCS7 antibody; SSI4 antibody; STAI4 antibody; STAT induced STAT inhibitor 4 antibody; STAT4 antibody; STATI4 antibody; Suppressor of cytokine signaling 4 antibody; Suppressor of cytokine signaling 7 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q8WXH5

Immunogen

Recombinant Human Suppressor of cytokine signaling 4 protein (1-270AA)

Raised in

Rabbit

Species Reactivity

Human, Mouse

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200

Background

SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. Substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Inhibits EGF signaling by mediating the degradation of the Tyr-phosphorylated EGF receptor/EGFR.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

SOCS4

Research Areas

Signal transduction