SOCS2 Antibody

Size

100ul

Clone Number

Aliases

CIS 2 antibody; CIS-2 antibody; CIS2 antibody; Cish 2 antibody; Cish2 antibody; Cytokine inducible SH2 protein 2 antibody; Cytokine-inducible SH2 protein 2 antibody; SOCS 2 antibody; SOCS-2 antibody; Socs2 antibody; SOCS2_HUMAN antibody; SSI 2 antibody; SSI-2 antibody; SSI2 antibody; STAT induced STAT inhibitor 2 antibody; STAT-induced STAT inhibitor 2 antibody; STATI 2 antibody; STATI2 antibody; Suppressor of cytokine signaling 2 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

O14508

Immunogen

Recombinant Human Suppressor of cytokine signaling 2 protein (1-198AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200

Background

SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS2 appears to be a negative regulator in the growth hormone/IGF1 signaling pathway. Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

SOCS2

Research Areas

Neuroscience; Immunology; Signal transduction