SNX9 Antibody

Size

100ug

Clone Number

Aliases

MST 155 antibody; MST155 antibody; MSTP 155 antibody; MSTP155 antibody; OTTHUMP00000040083 antibody; Protein SDP 1 antibody; Protein SDP1 antibody; SDP 1 antibody; SDP1 antibody; SH3 and PX domain containing protein 3A antibody; SH3 and PX domain containing protein SH3PX1 antibody; SH3 and PX domain-containing protein 1 antibody; SH3 and PX domain-containing protein 3A antibody; SH3PX1 antibody; SH3PXD3A antibody; SNX 9 antibody; SNX9 antibody; SNX9_HUMAN antibody; Sorting nexin 9 antibody; Sorting nexin-9 antibody; WASP interactor protein antibody; Wiskott Aldrich syndrome protein (WASP) interactor protein antibody; Wiskott Aldrich syndrome protein interactor protein antibody; WISP antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9Y5X1

Immunogen

Recombinant Human Sorting nexin-9 protein (85-200AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200

Background

Involved in endocytosis and intracellular vesicle trafficking, both during interphase and at the end of mitosis. Required for efficient progress through mitosis and cytokinesis. Required for normal formation of the cleavage furrow at the end of mitosis. Plays a role in endocytosis via clathrin-coated pits, but also clathrin-independent, actin-dependent fluid-phase endocytosis. Plays a role in macropinocytosis. Promotes internalization of TNFR. Promotes degradation of EGFR after EGF signaling. Stimulates the GTPase activity of DNM1. Promotes DNM1 oligomerization. Promotes activation of the Arp2/3 complex by WASL, and thereby plays a role in the reorganization of the F-actin cytoskeleton. Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate and promotes membrane tubulation. Has lower affinity for membranes enriched in phosphatidylinositol 3-phosphate.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

SNX9

Research Areas

Signal transduction