SNX18 Antibody

Size

100ul

Clone Number

Aliases

FLJ11997 antibody; FLJ32560 antibody; FLJ61062 antibody; MGC150827 antibody; MGC150829 antibody; SH3 and PX domain containing protein 3B antibody; SH3 and PX domain-containing protein 3B antibody; SH3PX2 antibody; SH3PXD3B antibody; SNAG 1 antibody; SNAG1 antibody; SNX18 antibody; SNX18_HUMAN antibody; Sorting nexin 18 antibody; Sorting nexin associated golgi protein 1 antibody; Sorting nexin-18 antibody; Sorting nexin-associated Golgi protein 1 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q96RF0

Immunogen

Recombinant Human Sorting nexin-18 protein (449-628AA)

Raised in

Rabbit

Species Reactivity

Human, Mouse

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200

Background

Involved in endocytosis and intracellular vesicle trafficking, both during interphase and at the end of mitosis. Required for efficient progress through mitosis and cytokinesis. Required for normal formation of the cleavage furrow at the end of mitosis. Plays a role in endocytosis via clathrin-coated pits, but also clathrin-independent, actin-dependent fluid-phase endocytosis. Plays a role in macropinocytosis. Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate and promotes membrane tubulation. Stimulates the GTPase activity of DNM2. Promotes DNM2 location at the plasma membrane.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

SNX18

Research Areas

Signal transduction