SMPD3 Antibody, Biotin conjugated

Size

100ug

Clone Number

Aliases

Cca1 antibody; Confluent 3Y1 cell-associated protein 1 antibody; Neutral sphingomyelinase 2 antibody; Neutral sphingomyelinase II antibody; NSMA2_HUMAN antibody; nSMase-2 antibody; nSMase2 antibody; SMPD3 antibody; Sphingomyelin phosphodiesterase 3 antibody; sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9NY59

Immunogen

Recombinant Human Sphingomyelin phosphodiesterase 3 protein (401-655AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA

Background

Catalyzes the hydrolysis of sphingomyelin to form ceramide and phosphocholine. Ceramide mediates numerous cellular functions, such as apoptosis and growth arrest, and is capable of regulating these 2 cellular events independently. Also hydrolyzes sphingosylphosphocholine. Regulates the cell cycle by acting as a growth suppressor in confluent cells. Probably acts as a regulator of postnatal development and participates in bone and dentin mineralization.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Biotin

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

SMPD3

Research Areas

Neuroscience