SMPD3 Antibody

Size

100ug

Clone Number

Aliases

Cca1 antibody; Confluent 3Y1 cell-associated protein 1 antibody; Neutral sphingomyelinase 2 antibody; Neutral sphingomyelinase II antibody; NSMA2_HUMAN antibody; nSMase-2 antibody; nSMase2 antibody; SMPD3 antibody; Sphingomyelin phosphodiesterase 3 antibody; sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9NY59

Immunogen

Recombinant Human Sphingomyelin phosphodiesterase 3 protein (401-655AA)

Raised in

Rabbit

Species Reactivity

Human, Mouse

Tested Applications

ELISA, IHC, IP; Recommended dilution: IHC:1:50-1:200, IP:1:200-1:2000

Background

Catalyzes the hydrolysis of sphingomyelin to form ceramide and phosphocholine. Ceramide mediates numerous cellular functions, such as apoptosis and growth arrest, and is capable of regulating these 2 cellular events independently. Also hydrolyzes sphingosylphosphocholine. Regulates the cell cycle by acting as a growth suppressor in confluent cells. Probably acts as a regulator of postnatal development and participates in bone and dentin mineralization.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

SMPD3

Research Areas

Neuroscience