SMO Antibody, Biotin conjugated

Size

100ug

Clone Number

Aliases

Frizzled family member 11 antibody; FZD11 antibody; Gx antibody; Gx protein antibody; Protein Gx antibody; SMO antibody; SMO_HUMAN antibody; SMOH antibody; Smoothened frizzled family receptor antibody; Smoothened homolog (Drosophila) antibody; Smoothened homolog antibody; Smoothened homolog precursor (SMO) (Gx protein) antibody; Smoothened seven transmembrane spanning receptor antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q99835

Immunogen

Recombinant Human Smoothened homolog protein (28-233AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA

Background

G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog\\\'s proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). Required for the accumulation of KIF7 and GLI3 in the cilia.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Biotin

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

SMO

Research Areas

Neuroscience; Signal transduction; Stem cells