SMG7 Antibody

Size

100ug

Clone Number

Aliases

breast cancer-associated antigen SGA-56M antibody; C1orf16 antibody; EST1 like protein C antibody; EST1 telomerase component homolog C antibody; EST1-like protein C antibody; EST1C antibody; ever shorter telomeres 1C antibody; FLJ23717 antibody; hSMG-7 antibody; nonsense mediated mRNA decay factor (C. elegans) antibody; Protein SMG7 antibody; SGA56M antibody; SMG 7 antibody; SMG-7 homolog antibody; Smg7 antibody; SMG7_HUMAN antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q92540

Immunogen

Recombinant Human Protein SMG7 protein (694-809AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:500-1:1000, IF:1:200-1:500

Background

Plays a role in nonsense-mediated mRNA decay. Recruits UPF1 to cytoplasmic mRNA decay bodies. Together with SMG5 is thought to provide a link to the mRNA degradation machinery involving exonucleolytic pathways, and to serve as an adapter for UPF1 to protein phosphatase 2A (PP2A), thereby triggering UPF1 dephosphorylation.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

SMG7

Research Areas

Epigenetics and Nuclear Signaling