SLUG Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects.

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human SLUG

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

29480

synonyms

SLUG; Zinc finger protein SNAI2; Neural crest transcription factor Slug; Protein snail homolog 2