SLU7 Antibody

Size

100ug

Clone Number

Aliases

9G8 antibody; hSlu7 antibody; MGC9280 antibody; Pre mRNA splicing factor SLU7 antibody; Pre-mRNA-splicing factor slu7 antibody; SLU 7 antibody; slu7 antibody; SLU7 splicing factor homolog (S. cerevisiae) antibody; SLU7 splicing factor homolog antibody; SLU7_HUMAN antibody; splicing factor antibody; Step II splicing factor SLU7 antibody; Zinc knuckle motif containing antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

O95391

Immunogen

Recombinant Human Pre-mRNA-splicing factor SLU7 protein (138-310AA)

Raised in

Rabbit

Species Reactivity

Human, Mouse

Tested Applications

ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200

Background

Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3\\\'-splice site to generate spliced mRNA and the excised lariat intron. Required for holding exon 1 properly in the spliceosome and for correct AG identification when more than one possible AG exists in 3\\\'-splicing site region. May be involved in the activation of proximal AG. Probably also involved in alternative splicing regulation.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

SLU7

Research Areas

Epigenetics and Nuclear Signaling; Cell biology; Metabolism; Signal transduction