ABCbiolab
SKU:ABCB10148
SLIB Rabbit Polyclonal Antibody
SLIB Rabbit Polyclonal Antibody
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Ab type
Primary antibody
Background
This gene encodes a member of the glucagon family of proteins. The encoded preproprotein is produced in the hypothalamus and cleaved to generate the mature factor| known as somatoliberin| which acts to stimulate growth hormone release from the pituitary gland. Variant receptors for somatoliberin have been found in several types of tumors| and antagonists of these receptors can inhibit the growth of the tumors. Defects in this gene are a cause of dwarfism| while hypersecretion of the encoded protein is a cause of gigantism. Alternative splicing results in multiple transcript variants| at least one of which encodes a preproprotein that is proteolytically processed.
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Host
Rabbit
Isotype
IgG
Immunogen
Synthesized peptide derived from human SLIB
Storage Stability
-20°C for 1 year
Concentration
1 mg/ml
MolecularWeight_Da
11880
synonyms
SLIB
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