SLC7A6 Antibody, HRP conjugated

Size

100ug

Clone Number

Aliases

SLC7A6 antibody; KIAA0245 antibody; Y+L amino acid transporter 2 antibody; Cationic amino acid transporter antibody; y+ system antibody; Solute carrier family 7 member 6 antibody; y(+)L-type amino acid transporter 2 antibody; Y+LAT2 antibody; y+LAT-2 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q92536

Immunogen

Recombinant Human Y+L amino acid transporter 2 protein (473-515AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA

Background

Involved in the sodium-independent uptake of dibasic amino acids and sodium-dependent uptake of some neutral amino acids. Requires coexpression with SLC3A2/4F2hc to mediate the uptake of arginine, leucine and glutamine. Also acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. Involved in the transport of L-arginine in monocytes. Reduces uptake of ornithine in retinal pigment epithelial (RPE) cells.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

HRP

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

SLC7A6

Research Areas

Neuroscience