SLC27A1 Antibody, FITC conjugated

Size

100ug

Clone Number

Aliases

SLC27A1 antibody; ACSVL5 antibody; FATP1Long-chain fatty acid transport protein 1 antibody; FATP-1 antibody; Fatty acid transport protein 1 antibody; EC 6.2.1.- antibody; Solute carrier family 27 member 1 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q6PCB7

Immunogen

Recombinant Human Long-chain fatty acid transport protein 1 protein (453-570AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

Background

Involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. The LFCA import appears to be hormone-regulated in a tissue-specific manner. In adipocytes, but not myocytes, insulin induces a rapid translocation of FATP1 from intracellular compartments to the plasma membrane, paralleled by increased LFCA uptake. May act directly as a bona fide transporter, or alternatively, in a cytoplasmic or membrane-associated multimeric protein complex to trap and draw fatty acids towards accumulation. Plays a pivotal role in regulating available LFCA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis. May be involved in regulation of cholesterol metabolism. Has acyl-CoA ligase activity for long-chain and very-long-chain fatty acids (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

FITC

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

SLC27A1

Research Areas

Cancer; Cardiovascular; Metabolism; Signal transduction