SLC25A33 Antibody, HRP conjugated

Size

100ug

Clone Number

Aliases

BMSC MCP antibody; BMSC-MCP antibody; Bone marrow stromal cell mitochondrial carrier protein antibody; HuBMSC MCP antibody; HuBMSC-MCP antibody; MGC4399 antibody; Mitochondrial carrier protein antibody; Novel mitochondrial carrier protein antibody; PNC1 protein antibody; Protein PNC1 antibody; S2533_HUMAN antibody; Slc25a33 antibody; Solute carrier family 25 member 33 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9BSK2

Immunogen

Recombinant Human Solute carrier family 25 member 33 protein (66-120AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA

Background

Mitochondrial transporter that imports/exports pyrimidine nucleotides into and from mitochondria (PubMed:25320081). Transports preferentially uracil, thymine, and cytosine (deoxy)nucleoside di- and triphosphates by an antiport mechanism (PubMed:25320081). Also transports guanine but not adenine (deoxy)nucleotides (PubMed:25320081). Is inhibited strongly by pyridoxal 5\'-phosphate, 4,7-diphenyl-1,10-phenanthroline, tannic acid, and mercurials (mercury dichloride, mersalyl acid, p-hydroxymercuribenzoate) (PubMed:25320081). Participates in mitochondrial genome maintenance, regulation of mitochondrial membrane potential and mitochondrial respiration (PubMed:20453889). Upon INS or IGF1 stimulation regulates cell growth and proliferation by controlling mitochondrial DNA replication and transcription, the ratio of mitochondria-to nuclear-encoded components of the electron transport chain resulting in control of mitochondrial ROS production (PubMed:20453889, PubMed:17596519). Participates in dendritic cell endocytosis and may associate with mitochondrial oxidative phosphorylation (PubMed:14715278).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

HRP

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

SLC25A33

Research Areas

Cancer; Metabolism; Signal transduction