SLC22A2 Antibody, HRP conjugated

Size

100ug

Clone Number

Aliases

SLC22A2 antibody; OCT2Solute carrier family 22 member 2 antibody; Organic cation transporter 2 antibody; hOCT2 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

O15244

Immunogen

Recombinant Human Solute carrier family 22 member 2 protein (48-135AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA

Background

Mediates tubular uptake of organic compounds from circulation. Mediates the influx of agmatine, dopamine, noradrenaline (norepinephrine), serotonin, choline, famotidine, ranitidine, histamin, creatinine, amantadine, memantine, acriflavine, 4-[4-(dimethylamino)-styryl]-N-methylpyridinium ASP, amiloride, metformin, N-1-methylnicotinamide (NMN), tetraethylammonium (TEA), 1-methyl-4-phenylpyridinium (MPP), cimetidine, cisplatin and oxaliplatin. Cisplatin may develop a nephrotoxic action. Transport of creatinine is inhibited by fluoroquinolones such as DX-619 and LVFX. This transporter is a major determinant of the anticancer activity of oxaliplatin and may contribute to antitumor specificity.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

HRP

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

SLC22A2

Research Areas

Metabolism; Signal transduction