SLC1A3 Antibody

Size

100ul

Clone Number

Aliases

EA6 antibody; EAA1_HUMAN antibody; EAAT1 antibody; Excitatory amino acid transporter 1 antibody; FLJ25094 antibody; GLAST antibody; GLAST-1 antibody; GLAST1 antibody; Glial high affinity glutamate transporter antibody; glutamate/aspartate transporter; high affinity; sodium-dependent antibody; High affinity neuronal glutamate transporter antibody; Slc1a3 antibody; Sodium dependent glutamate/aspartate transporter antibody; Sodium-dependent glutamate/aspartate transporter 1 antibody; Solute carrier family 1 (glial high affinity glutamate transporter) member 3 antibody; Solute carrier family 1 member 3 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P43003

Immunogen

Recombinant Human Excitatory amino acid transporter 1 protein (146-236AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:200-1:500, IF:1:100-1:500

Background

Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate (PubMed:7521911, PubMed:8123008, PubMed:20477940, PubMed:26690923, PubMed:28032905, PubMed:28424515). Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion (PubMed:20477940). Mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport (PubMed:20477940). Plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

SLC1A3

Research Areas

Others