SLC14A1 Antibody

Size

100ug

Clone Number

Aliases

blood group Kidd urea transporter antibody; erythrocyte antibody; HsT1341 antibody; HUT11 antibody; JK antibody; Kidd antibody; kidd (JK) blood group urea transporter B1 antibody; RACH1 antibody; Slc14a1 antibody; solute carrier family 14 (urea transporter) member 1 (Kidd blood group) antibody; Solute carrier family 14 member 1 antibody; Urea transporter 1 antibody; Urea transporter antibody; urea transporter B1 antibody; Urea transporter erythrocyte antibody; urea transporter JK glycoprotein antibody; UT B1 antibody; UT1 antibody; UT1_HUMAN antibody; UTE antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q13336

Immunogen

Recombinant Human Urea transporter 1 protein (1-51AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200

Background

Urea channel that facilitates transmembrane urea transport down a concentration gradient. A constriction of the transmembrane channel functions as selectivity filter through which urea is expected to pass in dehydrated form. The rate of urea conduction is increased by hypotonic stress. Plays an important role in the kidney medulla collecting ducts, where it allows rapid equilibration between the lumen of the collecting ducts and the interstitium, and thereby prevents water loss driven by the high concentration of urea in the urine. Facilitates urea transport across erythrocyte membranes. May also play a role in transmembrane water transport, possibly by indirect means.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

SLC14A1

Research Areas

Cancer; Cardiovascular; Metabolism; Signal transduction